Bicalutamide

Bicalutamide is an anti-androgen, used for prostate cancer either alone or as an adjunct to other therapy, according to the clinical circumstances. It inhibits the tumour "flare"which may occur after commencing gonadorelin analogue (e.g diethylstilbestrol) administration.

Brands
CASODEX CALUTIDE
Adult Dose
Dose: 50 mg
Single Dose: 50 (50)
Frequency: As recommended.
Route: PO
Instructions: Daily with orchidectomy or gonadorelin therapy.
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Non Steroidal Antiandrogen. . The Molecular Weight of Bicalutamide is 430.40.
Contraindications
Bicalutamide is contraindicated in conditions like Hypersensitivity.
Effects
The severe or irreversible adverse effects of Bicalutamide, which give rise to further complications include Congestive heart failure, Angina.The symptomatic adverse reactions produced by Bicalutamide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Tiredness, Fatigue, Nausea, Vomiting, Anorexia, Diarrhea, Fever, Anxiety, Nervousness, Chills, Rashes, Confusion, Dyspepsia, Depression, Weight gain, Somnolence, Cough, Hot flushes, Xerostomia.
Indications
Bicalutamide is primarily indicated in conditions like Prostatic cancer, and can also be given in adjunctive therapy as an alternative drug of choice in Prostate cancer.
Interactions
No data regarding the interactions of Bicalutamide was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store at room temperature, Below 30°C. Protect from Moisture.
Warnings
Bicalutamide should be used with caution in patients with moderate to severe hepatic impairment. Avoid use in females and childrens.
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