Artemisinin

Artemisinin is an antimalarial, belongs to sesquiterpene lactone endoperoxide group. Artemisinin is derived from the weed qing hao (Artemisia annua), also called as wormwood or annual wormwood. The medicinal value has been known for more than 2000 years. It and related drugs are the most rapidly acting, effective and safe drugs for the treatment of severe malaria, including infection due to chloroquine and mutidrug-resistant strains of Plasmodium falciparum. It should not be used for prophylaxis of malaria or treatment of mild attacks.

Brands
COTECXIN HITECXIN
Adult Dose
Dose: 100 to 200 mg/day
Single Dose: 150 (150)
Frequency: As recommended.
Route: oral
Instructions:
Neonatal
Paedriatic
Characteristics
. It is of Natural origin and belongs to Sesquiterpene lactone. . The Molecular Weight of Artemisinin is 282.30.
Contraindications
Artemisinin is contraindicated in conditions like Malaria prophylaxis.
Effects
The severe or irreversible adverse effects of Artemisinin, which give rise to further complications include Jaundice, Neurotoxicity, Cardiovascular toxicity.The signs and symptoms that are produced after the acute overdosage of Artemisinin include Cardiovascular disturbances.The symptomatic adverse reactions produced by Artemisinin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Nausea, Vomiting, Fever, Abdominal cramps, Tinnitus, Abdominal pain, Skin rashes, Sweating, Pruritus, Hypotension, Somnolence, Darkening of urine, Decreased reticulocytes, Transient low fever.
Indications
Artemisinin is primarily indicated in conditions like Chloroquine resistant malaria, Complicated and severe malaria, Uncomplicated malaria.
Interactions
No data regarding the interactions of Artemisinin was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and Cardiac / Hypertensive Patients.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab, Caps Store . Protect from Sunlight, Moisture and Heat.
Warnings
Care should be taken when using to treat the women being pregnant with in three months or patients with vomiting severely.
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