Arbekacin

Arbekacin is an antibacterial agent, belongs to aminoglycoside antibiotics. Arbekacin is a derivative of dibekacin and has general properties similar to those of gentamicin. Arbekacin is used parenterally in the treatment of serious infections due to methicillin-resistant Staphylococcus aureus.

Brands
Adult Dose
Neonatal
Paedriatic
Characteristics
. It is of Semi Synthetic origin and belongs to Streptamine. . The Molecular Weight of Arbekacin is 552.60. Its pKa is 8.1.
Contraindications
Arbekacin is contraindicated in conditions like Hypersensitivity.
Effects
The severe or irreversible adverse effects of Arbekacin, which give rise to further complications include Ototoxicity, Reversible renal tubular injury.Arbekacin produces potentially life-threatening effects which include Neuromuscular blockage, Nephrotoxicity. which are responsible for the discontinuation of Arbekacin therapy.The signs and symptoms that are produced after the acute overdosage of Arbekacin include Nephrotoxicity, Neuromuscular blockade, Ototoxicity.The symptomatic adverse reactions produced by Arbekacin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Skin rashes.
Indications
Arbekacin is primarily indicated in conditions like Pneumonia, Septicaemia.
Interactions
No data regarding the interactions of Arbekacin was found.
Interfrence
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Special precaution is required when using in elderly patients with significant impairment of renal function because high serum concentration of arbekacin might cause renal or ototoxicity. In patients with renal insufficiency the dosage and dose interval should be adjusted by monitoring the serum concentration. Arbekacin should be administered in separate drip infusion when co-administration of different drug is contemplated.
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