Magnesium Trisilicate

Magnesium Trisilicate is a non-systemic antacid used in the treatment of peptic ulceration. Neutralization of acid is slow in onset but relatively prolonged due to adsorbent properties of silicic acid formed in the stomach. It has a lexative effect in larger doses. Danger of magnesium toxicity in patients with renal failure.


Adult Dose
Dose: 10 ml
Single Dose: 10 (10)
Frequency: 6 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Characteristics
. The Molecular Weight of Magnesium Trisilicate is 260.90.
Contraindications
Magnesium Trisilicate is contraindicated in conditions like Osteomalacia,Hypophosphataemia,Kidney disease.
Effects
The severe or irreversible adverse effects of Magnesium Trisilicate, which give rise to further complications include Hypermanganesemia, Kidney stones.The symptomatic adverse reactions produced by Magnesium Trisilicate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Constipation, Nausea and vomiting.
Indications
Magnesium Trisilicate is primarily indicated in conditions like Dyspepsia, Heart burn, Hyperacidity.
Interactions
Magnesium Trisilicate is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementFamotidineBioavailability of Famotidine is decreased when administered with antacids (e.g Magnesium Trisilicate)Hydroxyquinolone SulphateIron Hydroxide Poly Maltose ComplexAntacids and mineral supplements containing Ca and Mg ( antacid like Magnesium Trisilicate) leads to impaired absorption of Iron These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab, Caps Store Below 40°C. Protect from Sunlight and Moisture.
Warnings
Donot exceed prescribed dose because it will cause diarrhea.Magnesium trisilicate should be use with caution in patients with renal impairment, stomach disorders and allergies
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