CLAFORAN CLAFORAN CLAFORAN FORAX FORAX FORAX HEXIME HEXIME HEXIME TAXIME TAXIME TAXIME ALBAXIM ALBAXIME ALBAXIME ALBAXIME CEFTAX CEFTAX CEFTAX TAXIBEN TAXIBEN TAXIBEN CEFOCENT CEFOCENT CEFOCENT RITAGE RITAGE CEFOTAX CEFOTAX CEFOTAX QCEF QCEF QCEF WINTAX WINTAX WINTAX CEFTORINGE CEFTORINGE D-FRON D-FRON D-FRON CLAFTAX CLAFTAX CLAFTAX CETAXIMA FOTAX FOTAX FOTAX FARAXIME FARAXIME FARAXIME SAMCEF SAMCEF SAMCEF SAMCEF SAMCEF SAMCEF EPOTAZIME EPOTAZIME EPOTAZIME CLAGEN CLAGEN CLAGEN FEDRATOX FEDRATOX FEDRATOX TAXFO TAXFO TAXFO XIMGAL XIMGAL SPORONIL SPORONIL SPORONIL CEFOXIM CEFOXIM CEFOXIM CEFACRON CEFACRON CEFACRON DAYTAXIME DAYTAXIME DAYTAXIME KC-TEX KC-TEX KC-TEX EXEF EXEF EXEF NOSPOR NOSPOR NOSPOR SEFOBAN SEFOBAN SEFOBAN NOVOSEF NOVOSEF NOVOSEF NOVOSEF NOVOSEF NOVOSEF CLAVOX CLAVOX CLAVOX L-FOTAX L-FOTAX L-FOTAX ZEREF-S ZEREF-S ZEREF-S CEFOGATE CEFOGATE CEFOGATE BIOXIM BIOXIM BIOXIM CEFOMED CEFOMED CEFOMED MOLELANT MOLELANT MOLELANT SHINTAX CEFAX CEFAX SETEX SETEX SETEX CEFOTAXIME BAXIM BAXIM BAXIM SAJTOX SAJTOX SAJTOX CEF-SO CEF-SO CEF-SO ORTAXIME ORTAXIME ORTAXIME OBIXIME OBIXIME OBIXIME N-ZEE N-ZEE N-ZEE N-ZONE N-ZONE N-ZONE CEFOMERC CEFOMERC CEFOMERC CEPHRONATE CEPHRONATE CEPHRONATE EVOTAXIME EVOTAXIME EVOTAXIME TAXIRON TAXIRON TAXIRON TAXIRON PCEF PCEF PCEF CEFWISE CEFWISE CEFWISE IXIM IXIM IXIM PULCEF PULCEF PULCEF TUFZONE TUFZONE TUFZONE BIOLOG BIOLOG BIOLOG CYOX CYOX CYOX BREETEX BREETEX BREETEX YORKER YORKER YORKER FASTIMAX FASTIMAX FASTIMAX GEN-3 GEN-3 GEN-3 CLIVER CLIVER CLIVER CEFON CEFON CEFON BACXIME BACXIME BACXIME FURITAX FURITAX FURITAX SWIFTAX SWIFTAX SWIFTAX ZAFIXIME ZAFIXIME ZAFIXIME WITAX WITAX WITAX SUPERIXIME ONEXIN ONEXIN ONEXIN ADWOTEX ADWOTEX ADWOTEX WONTAXIME WONTAXIME WONTAXIME EAXIRON EAXIRON EAXIRON ELKOTAX ELKOTAX ELKOTAX CEFTIM CEFTIM CEFTIM GENCEF FOXIME FOXIME FOXIME CLACEF CLACEF MB-CEF MB-CEF MB-CEF POLYTAX POLYTAX POLYTAX CEFTREX CEFTREX CEFTREX CEFOTAM CEFOTAM SPIROSINE OCECLAF OCECLAF KALFOXIM KALFOXIM KALFOXIM KALFOXIM EMEXIN EMEXIN EMEXIN BIOTAXIME BIOTAXIME ROCETRAX ROCETRAX ROCETRAX STAFRON STAFRON STAFRON RACLIF RACLIF RACLIF BIDZIME AXIFINE AXIFINE CEFCAN CEFCAN CEFCAN SHIFACRON SHIFACRON SHIFACRON SILVAXIME SILVAXIME SILVAXIME CEFTI CEFTI CEFTI NAWOTAX CEFORIN CEFORIN CEFORIN SURGITEC SURGITEC SURGITEC SUPRAX SUPRAX SUPRAX SUPRAX UNEED MACFRAN MACFRAN MACFRAN CYNOTAX CYNOTAX TRAXIM TRAXIM TRAXIM TRAXIM TRAXIM TRAXIM HYPERTAX HYPERTAX HYPERTAX TREAT NESTOX NESTOX NESTOX NOVATEX NOVATEX NOVATEX CLIFRID CLIFRID CAFRAN CAFRAN CAFRAN XEMEG XEMEG VEGACEFT VEGACEFT VEGACEFT AWABROD AWABROD CEFDOX CEFDOX CEFDOX FOTRI FOTRI FOTRI JAFOTAX JAFOTAX GRAXIME GRAXIME SPEEDRO SPEEDRO SPEEDRO BOSCEF BOSCEF BOSCEF KECEF KECEF KECEF TRIGOREN TRIGOREN UNITOXIME UNITOXIME UNITOXIME PURE-XEM PURE-XEM PURE-XEM CEFORAINS CEFORAINS CEFORAINS ZINTAXIME ZINTAXIME ZINTAXIME RIEL RIEL RIEL CEFTIFIXE MEDOXIN MEDOXIN MEDOXIN TRENCH TRENCH NITAXIM NITAXIM NITAXIM KUMAND KUMAND KUMAND ZYMACEF ZYMACEF ZYMACEF EFIXONE EFIXONE EFIXONE CEUTICSAXIME CEUTICSAXIME CEUTICSAXIME FOTAMAK FOTAMAK FOTAMAK ALITOX ALITOX ALITOX MEDIFRAN MEDIFRAN MEDIFRAN CEFOCIN CEFOCIN CEFOCIN HYLAFORM HYLAFORM HYLAFORM DORTIS DORTIS DORTIS CEFOGREEN CEFOGREEN CEFOGREEN ALGIXIM ALGIXIM ALGIXIM PERT PERT PERT GENEXIME GENEXIME MAHIR MAHIR MAHIR INSTAX INSTAX INSTAX AFRAN AFRAN AFRAN TACZIN TACZIN TACZIN LIFTAX LIFTAX LIFTAX MYTAX MYTAX MYTAX SUNTAC SUNTAC SUNTAC MEDFOTAX MEDFOTAX MEDFOTAX ASTETAXM ASTETAXM ASTETAXM NEATX NEATX NEATX ARATAXIME ARATAXIME ARATAXIME SPORTAX SPORTAX VICOFRON VICOFRON VICOFRON OLSON OLSON OLSON CEMETAX CEMETAX CEMETAX CEFTISAV CEFTISAV CEFTISAV KEPREX KEPREX KEPREX BAXFORAN BAXFORAN FUSTEXIN FUSTEXIN CEFABEST CEFABEST CEFABEST

Dose: 3 to 6 g/dose
Single Dose: 4.5 (4.5)
Frequency: 24 hourly
Route: intra abnominal infection
Instructions:

Dose:
Single Dose:
Frequency:
Route:
Instructions:

Dose: 100 to 200 mg
Single Dose: 150 (150)
Frequency: 8 hourly
Route: Intra Muscular
Instructions: 2 to 4 divided doses. and 200mg dose given in 24hr daily.

Cefotaxime Na is the derivative of Cefotaxime. It is of Semi Synthetic origin and belongs to Cephem carboxylate. It belongs to Peptidoglycan synthesis inhibitor pharmacological group on the basis of mechanism of action and also classified in Antibiotic, Cephalosporin-3rd Gen pharmacological group.The Molecular Weight of Cefotaxime is 478.50. Its pKa is 3.75.

Cefotaxime is contraindicated in conditions like Renal diseases,Hypersensitivity.

The severe or irreversible adverse effects of Cefotaxime, which give rise to further complications include Thrombocytopenia, Eosinophilia, CNS toxicity, Leukopenia.Cefotaxime produces potentially life-threatening effects which include Pseudomembranous colitis. which are responsible for the discontinuation of Cefotaxime therapy.The signs and symptoms that are produced after the acute overdosage of Cefotaxime include Encephalopathy.The symptomatic adverse reactions produced by Cefotaxime are more or less tolerable and if they become severe, they can be treated symptomatically, these include Vertigo, Nausea, Vomiting, Diarrhea, Fever, Rashes, Pruritus, Hallucination, Thrombophlebitis, Pain at injection site.

Cefotaxime is primarily indicated in conditions like Arrhythmias after myocardial infarction, Bacteremia, Cellulitis, Gonorrhoea, Gynecological infections, Infilteration anaesthesia, Meningitis, Obstetric infections, Osteomyelitis, Peritonitis, Respiratory tract infections, Surgical prophylaxis, Urinary tract infection.

Cefotaxime is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAmikacin (Sulphate)synergestic effect for pseudomonas aeruginosaAzlocillin (Na)Fosfomycinsynergestic effect aganist methicillin resistant staphylococci.Frusemide or Furosemidewhen cefotaxime combine with lasix or other diuretic have a risk of nephrotoxicity.GentamicinMezlocillinProbenecidreduce renal clearance of cefotaxime resulting in higher plasma conc.Tobramycinsynergestic effect for pseudomonas aeruginosa These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

False +ve results in Redox method for determining the presence of urine glucose. Affects the bioassay of gentamicin.

Drug should not be given to Pregnant Mothers, and patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dry Powder for Inj Store at room temperature, Below 30°C. Protect from Sunlight and Heat. Prefrozen Inj Store Below -20°C. Freezing is recommended. Thawed Store at room temperature or refrigerator. Use within 10 days if refrigerated and within 24 hrs if kept at room temperature.

Cefotaxime should be used with caution in patients with impaired kidney or liver function. Appropriate measure should be taken if secondary infection occurs.