Bromohexine

Bromohexine is a mucolytic agent. Bromohexine is used in the treatment of respiratory disorders associated with reproductive cough, emphysema with bronchitis, pneumoconiosis, chronic inflammatory pulmonary conditions and bronchitis and other conditions where tenacious mucous is problem.

Brands
ERYBRON ERYBRON BISOLVON MUCOF
Adult Dose
Dose: 10 ml
Single Dose: 10 (10)
Frequency: 8 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Characteristics
Bromohexine also known as Bromhexine. Bromhexine Hcl is the derivative of Bromohexine. It is of Synthetic origin. . The Molecular Weight of Bromohexine is 376.13.
Contraindications
Bromohexine is contraindicated in conditions like Pregnancy,Hypersensitivity to the drug.
Effects
The symptomatic adverse reactions produced by Bromohexine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Sweating, Skin RashX, Bronchospasm, GI disturbance.
Indications
Bromohexine is primarily indicated in conditions like Dry eye syndrome, Productive cough, Respiratory tract disorders.
Interactions
No data regarding the interactions of Bromohexine was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tabs, syrups Store in a well closed container, Below 30°C. Protect from Sunlight and Moisture.
Warnings
Bromhexine should be avoided or used with caution in patients undergoing anaesthesia with cyclopropane, halothane or other halogenated anaesthetics, as it may induce ventricular fibrillation. An increased risk of arrhythmias may also occur if given to patients receiving cardiac glycosides, quinidine, or tricyclic antidepressants. Hypokalaemia may be induced by higher than recommended doses of beta-agonists, especially in patients receiving digitalis glycosides or diuretics, or those who are prone to cardiac dysrhythmias. Caution should be observed in patients with gastric ulcers due to the mucolytic action of bromhexine hydrochloride. In addition, care should be observed in patients suffering from cardiovascular diseases, i.e., ischaemic heart disease; arrhythmias or tachycardia; and occlusive vascular disorders, including arteriosclerosis, hypertension or aneurysms. Anginal pain may be precipitated in patients suffering from angina pectoris. Care is also required when bromhexine is given to patients with diabetes mellitus or closed-angle glaucoma. Caution is also needed in patients with convulsive disorders.
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