Carfecillin (Na)

Carfecillin (Na) is antibiotic and is used to treat bacterial infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieve by taking the drug at regular interval of time throughout the day and night as prescribed. Carfecillin (Na) is important to take the drug for the full time period as prescribed. If you discontinue the drug it may result in ineffective treatment.


Brands
Adult Dose
Dose: 7.14 to 14.28 mg/kg
Single Dose: 11 (10.71)
Frequency: 8 hourly
Route: PO
Instructions: -
Neonatal
Dose: 10 to 20 mg/kg
Single Dose: 15 (15)
Frequency: 8 hourly
Route: Oral
Instructions: -
Paedriatic
Dose: 10 to 20 mg/kg
Single Dose: 15 (15)
Frequency: 8 hourly
Route: Oral
Instructions: -
Characteristics
. It is of Synthetic origin and belongs to Penicillinate. It belongs to Peptidoglycan synthesis inhibitor pharmacological group on the basis of mechanism of action and also classified in Antibiotic, Penicillin pharmacological group.The Molecular Weight of Carfecillin (Na) is 476.50. Its pKa is 2.9.
Contraindications
Carfecillin (Na) is contraindicated in conditions like Bacteremia,Sepsis.
Effects
Carfecillin (Na) produces potentially life-threatening effects which include Hypersensitivity rash. which are responsible for the discontinuation of Carfecillin (Na) therapy.The symptomatic adverse reactions produced by Carfecillin (Na) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, GI upset.
Indications
Carfecillin (Na) is primarily indicated in conditions like Urinary tract infection.
Interactions
No data regarding the interactions of Carfecillin (Na) was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Adequate fluid intake must be maintained during clodronate treatment. This is particularly important when administering clodronate as intravenous infusion and in the patients with hypercalcemia or renal failure. Intravenous administration of doses notably higher than those recommended may cause severe renal damage especially if the infusion rate is too high.
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