Gadodiamide

Gadodiamide is a non-ionic paramagnetic agent. Gadodiamide is used for enhancement in imaging of cranial and spinal structures.


Brands
Adult Dose
Dose: 0.2 ml/kg body weight
Single Dose: 0.2 (0.2)
Frequency: As recommended.
Route: IV
Instructions:
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin. . The Molecular Weight of Gadodiamide is 573.10. It is weakly acidic drug.
Contraindications
Gadodiamide is contraindicated in conditions like Anaemia,Asthma,Hypersensitivity to the drug.
Effects
The severe or irreversible adverse effects of Gadodiamide, which give rise to further complications include Hypotension, Hypotension, Paresthesia, Transient elevation of serum iron & bilirulin, Localized Pain.Gadodiamide produces potentially life-threatening effects which include Shock. which are responsible for the discontinuation of Gadodiamide therapy.The symptomatic adverse reactions produced by Gadodiamide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Pain, Allergic reactions, Taste disturbance, Nausea and vomiting, Sensation of warmth, dizziness.
Indications
Gadodiamide is primarily indicated in conditions like Diagnostic procedures, Non ionic contrast medium.
Interactions
No data regarding the interactions of Gadodiamide was found.
Interfrence
May Interfere with colorimetric methods for measuring serum calcium consentunations, resulting in falsely low measurnments.
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Liver Malfunction, and Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
IV Inj
Warnings
The usual precaution measures for MRI examination should be taken, such as exclusion of pacemakers and ferro-magnetic implants.To enable immediate action in emergencies, the necessary medicinal products and equipment for intubation and adequate ventilation support must be immediately available. If hypersensitivity reactions occur, the administration of the contrast medium must be discontinued immediately.
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