Guaifenesin

Guaifenesin is expectorant. Chemically Guaifenesin is 3-(o-methoxyphenoxy)-1, 2-propanediol. It reduces the viscosity of phlegm and mucous in the lungs. It enables coughing up of mucous.


Adult Dose
Dose: 200 to 400 mg
Single Dose: 300 (300)
Frequency: 4 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Characteristics
Guaifenesin also known as Glyceryl Guaiacolate. . It is of Synthetic origin and belongs to Propanediol. . The Molecular Weight of Guaifenesin is 198.22.
Contraindications
Guaifenesin is contraindicated in conditions like Hypersensitivity reactions.
Effects
The symptomatic adverse reactions produced by Guaifenesin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Rashes, Nausea and vomiting, Stomach upset, Stomach upset, Stomach pain, dizziness, rashes.
Indications
Guaifenesin is primarily indicated in conditions like Productive cough.
Interactions
Guaifenesin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementSodium AcetateAlkalization of the urine decreases the urinary excretion increases the elimination half-life of Guaifenesin.ModeratePatients should be monitored for toxic effects such as tremor, anxiety, insomnia, irritability, or nervousness. Dosage reductions may be required. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Syrup Store Below 40°C. Do not Freeze. Protect from Sunlight and Moisture. Tab Store Below 40°C. Protect from Sunlight and Moisture.
Warnings
Guaifenesin should not use in excessive amount because may cause nausea and vomiting. If cough persists for more than one week, accompanied by high fever, rash or headache, consult the physician. Use caution when driving, operating machinery, or performing other hazardous activities. Guaifenesin may cause dizziness. If you experience dizziness, avoid these activities.
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