Strychnine

Strychnine is extremely poisonous alkaloid obtained chiefly from the seeds of Strychnos nux vomica and other species of Strychnos. Strychnine is used in the investigation of mode of action of anticonvulsant drugs.

Brands

VIKONON FORTE

Adult Dose

Neonatal

Paedriatic

Characteristics

. It is of Natural origin. . The Molecular Weight of Strychnine is 334.42.

Contraindications

Strychnine is contraindicated in conditions like Excessive reflex irritability,Acute inflammatory conditions of the spinal cord.

Effects

The severe or irreversible adverse effects of Strychnine, which give rise to further complications include Tremors, Severe spasm.Strychnine produces potentially life-threatening effects which include Respiratory arrest, Painful convulsions. which are responsible for the discontinuation of Strychnine therapy.The symptomatic adverse reactions produced by Strychnine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Twitching, Stiffiness of face and legs.

Indications

Strychnine can be given in adjunctive therapy as an alternative drug of choice in Bronchial asthma, Constipation, Diabetes mellitus, Diarrhoea, Non-ketonic hyperglycenaemia, Opthalmic disease, Pain, Urinary tract disorder.

Interactions

No data regarding the interactions of Strychnine was found.

Interfrence

Risks

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Storage

Warnings

Strychnine is a potent convulsant. Use impervious clothing, gloves and face shields when handling it.

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