Meclizine

Meclizine is a piperazine derivative, is a sedating anti-histimine with antimuscarinic properties. Meclizine is mainly used for its antiemetic action which may last for up to 24 hours. Meclizine is used in the prevention and treatment of nausea and vomiting associated with variety of conditions including motion sickness and for symptomatic treatment of vertigo and Meclizine is also used for the symptomatic relief of hypersensitivity reactions and pruritic skin disorders.

Brands
NAVIDOXINE MECLO SEVIDOXINE WEDOXINE
Adult Dose
Dose: 0.119 to 0.476 mg/kg
Single Dose: 0.3 (0.2975)
Frequency: 3 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Dose: 6.25 mg
Single Dose: 6.2 (6.25)
Frequency: 24 hourly
Route: 6-Feb
Instructions:
Characteristics
Meclizine also known as Meclozine, Meclozine. . It is of Synthetic origin and belongs to Piperizine dervative. . The Molecular Weight of Meclizine is 390.95.
Contraindications
Meclizine is contraindicated in conditions like Hypersensitivity to any component of product.
Effects
The severe or irreversible adverse effects of Meclizine, which give rise to further complications include Tachycardia, Palpitation, Urinary retention, Visual hallucination.The signs and symptoms that are produced after the acute overdosage of Meclizine include Convulsions, Hallucinations, Respiratory paralysis.The symptomatic adverse reactions produced by Meclizine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Drowsiness, Anorexia, Diarrhea, Insomnia, Nervousness, Dry mouth, Blurred vision, Rashes, Nausea and vomiting, nervousness.
Indications
Meclizine is primarily indicated in conditions like Dizziness, Motion sickness, Nausea and vomiting, Vertigo, Vestibular disturbances.
Interactions
No data regarding the interactions of Meclizine was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store Below 40°C. Protect from Sunlight and Moisture.
Warnings
Patient should observe caution while driving or performing other task requiring alertness because it may produce dizziness. Meclizine should be used with caution in patients with asthma, glaucoma, obstructive disease of gastrointestinal (GI) tract.
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