Meloxicam

Meloxicam is NSAID (nonsteroidal anti-inflammatory drug) of oxicam family. It has anti-infalmmatory, analgesic and antipyretic properties. Meloxicam is used to reduce fever and inflammation or swelling and to relieve pain. Meloxicam is used to treat pain, swelling and stiffness associated with arthritis..


Adult Dose
Dose: 15 mg
Single Dose: 15 (15)
Frequency: As recommended.
Route: PO
Instructions:
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Dexicamdexicative. . The Molecular Weight of Meloxicam is 351.40. Its pKa is 1.1-4.2.
Contraindications
Meloxicam is contraindicated in conditions like Renal failure,Hepatic failure,Rectal bleeding,Proctitis,Hemorrhoids.
Effects
The severe or irreversible adverse effects of Meloxicam, which give rise to further complications include Angioedema, Ulceration, Bleeding, Angioedema, GI perforation.The symptomatic adverse reactions produced by Meloxicam are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Rashes, Urticaria, Pruritus, Photosensitivity, dizziness.
Indications
Meloxicam is primarily indicated in conditions like Ankylosing spondylitis, Osteoarthritis, Rheumatoid arthritis.
Interactions
Meloxicam is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholCyclosporin APentoxifyllinePhenylbutazone Phenytoin (Na)VORICONAZOLEVoriconazole may increase the serum concentration of meloxicam by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects Vortioxetineeither increases effects of the other by anticoagulationmonitor closelyZidovudine These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Complete blood cell count
Risks
Drug should not be given to Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
It should not be given to in case of nasal polyps associated with bronchospasm, aspirin induced (high risk of severe allergic reaction), previous allergic/anaphylactic reaction to aspirin or NSAIDs. Risk benefits should be considered under the following problems: alcoholism, gastrointestinal bleeding, peptic ulcer disease, asthma, compromised cardiac function, congestive heart disease, edema, hypertension, hepatic and renal function impairment. Haemmorrhoids or rectal bleeding,
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