Mepivacaine

Mepivacaine (HCl) is amide type local anesthetic. It consists of an aromatic ring connected by an intermediate chain, including an ester or amide to an ionizable group, usually a tertiary amine. The actions and effects similar to that of lidocaine. It works by preventing nerves from transmitting painful impulses to brain which creates temperory anesthesia.

Brands
ENVIT MEPICAN
Adult Dose
Neonatal
Paedriatic
Characteristics
Mepivacaine (HCl) is the derivative of Mepivacaine. It is of Synthetic origin and belongs to Ester. . The Molecular Weight of Mepivacaine is 282.80. Its pKa is 7.7.
Contraindications
Mepivacaine is contraindicated in conditions like Hypersensitivity.
Effects
The severe or irreversible adverse effects of Mepivacaine, which give rise to further complications include Convulsions, Cardiac arrhythmias, Allergic reactions, Chest pain, Tremors.Mepivacaine produces potentially life-threatening effects which include Coma, Convulsions, Respiratory Failure, Cardiac Arrest. which are responsible for the discontinuation of Mepivacaine therapy.The signs and symptoms that are produced after the acute overdosage of Mepivacaine include Skin eruptions.The symptomatic adverse reactions produced by Mepivacaine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Excitement, Anxiety, Restlessness, Tremors, Nervousness, Blurred vision, Nausea and vomiting, Numbness, Backache.
Indications
Mepivacaine is primarily indicated in conditions like Anesthesia, Caudal anaesthesia, Epidural anaesthesia, and can also be given in adjunctive therapy as an alternative drug of choice in Infilteration anaesthesia, Nerve block.
Interactions
No data regarding the interactions of Mepivacaine was found.
Interfrence
Risks
Drug should not be given to Cardiac / Hypertensive Patients.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj
Warnings
Avoid mepivacain in patient with known hypersensitivity. It should be given with caution to the elderly, to debilitated, to children, patients with epilepsy, impaired cardiac conduction or respiratory function, shock or liver damage. It might be ototoxic and should not be instilled into the middle ear. The application of local anesthetics to the skin for prolonged period or to the extensive area should be avoided. Avoid alcohol. Donot drive because Mepivacaine may cause dizziness.
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