TARISIN FLUNI

Dose: 2 sprays
Single Dose: 2 (2)
Frequency: 12 hourly
Route: Inh
Instructions: If needed, this dose may be increased to 2 sprays in each nostril 3 times a day._x000D_Maximum total daily doses should not exceed 8 sprays in each nostril.

. It is of Synthetic origin and belongs to Steroids. . The Molecular Weight of Flunisolide is 434.50.

Flunisolide is contraindicated in conditions like Septic shock,Sickle cell disease.

The severe or irreversible adverse effects of Flunisolide, which give rise to further complications include Hypersensitivity reactions.The signs and symptoms that are produced after the acute overdosage of Flunisolide include Cardiovascular collapse, Adrenal suppression.The symptomatic adverse reactions produced by Flunisolide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Hypersensitivity reactions, Dryness, Irritation of nasal mucosa, Taste disturbanceX.

'Flunisolide is primarily indicated in conditions like Adrenal insufficiency, Allergic rhinitis, Angioedema, Haemolytic anaemia, Rhinitis, and can also be given in adjunctive therapy as an alternative drug of choice in Asthma, Beheet''s syndrome, Crohn''s disease, Lupus erythematosus, Vasculitis.'

Flunisolide is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementKetoconazolePhenobarbitonePhenytoin (Na)RifampicinStanozololVORICONAZOLEVoriconazole may increase the serum concentration of flunisolide by decreasing its metabolism. Monitor for changes in the therapeutic and adverse effects of flunisolide if voriconazole is initiated, discontinued or dose changed. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Inhaler Store Below 40°C. Protect from Sunlight and Heat.

Flunisolide should be used with caution in patients with active tuberculosis infection of respiratory tract or in untreated fungal, bacterial or systemic viral infections. Corticosteroids should only be used systemically with great caution in the presence of congestive heart failure (CHF), recent myocardial infraction (MI), hypertension, diabetes mellitus, epilepsy, glaucoma, hypothyroidism, liver failure, osteoporosis, peptic ulceration or renal impairment. Children may be at increase risk of some adverse effects, corticosteroid causes growth retardation and prolonged use is rarely justified. Passive immunization is recommended to non-immune patients who do come in contact with chickenpox or measles. Live vaccine should not be given to patients receiving high dose systemic corticosteroid therapy nor for atleast 3months afterwards, killed vaccine or toxoids may be given, although the response may be attenuated. During prolong treatment with corticosteroids, patients should be examined regularly, sodium intake may need to be reduced and calcium and potassium supplement may be necessary. Patient should carry cards given full details of their corticosteroid therapy. Avoid use during pregnancy. Use nasal steroids with caution until healing has occurred.