Betacarotene

Betacarotene is a carotenoid precursor of vitamin A. which is a fat soluble vitamin and is essential for normal visual function, for healthy skin and for growth. Betacarotene is used in the treatment of vitamin A deficiencies.


Adult Dose
Dose: 30 to 300 mg
Single Dose: 160 (165)
Frequency: As recommended.
Route: PO
Instructions: As Required
Neonatal
Paedriatic
Characteristics
. It is of Natural origin and belongs to Retinol. . The Molecular Weight of Betacarotene is 536.90.
Contraindications
Betacarotene is contraindicated in conditions like Hypersensitivity reactions.
Effects
The symptomatic adverse reactions produced by Betacarotene are more or less tolerable and if they become severe, they can be treated symptomatically, these include Loose stools, Arthralgia, Skin discoloration, Bruising.
Indications
Betacarotene is primarily indicated in conditions like Erythropoietic protoporphyria, Polymorphous light eruption, Vitamin A deficiency, and can also be given in adjunctive therapy as an alternative drug of choice in Ischaemic heart disease.
Interactions
Betacarotene is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementLycopenemay enhance the absorpion of lycopene These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Powder Store in a well closed container, Below 25°C. Protect from Sunlight.
Warnings
betacarotene should be used with caution in patients with renal disease or hepatic disease . Renal impairment may lead to increased betacarotene concentrations. Hypervitaminosis A is characterized by fatigue, malaise, irritability, psychiatric changes mimicking severe depression or schizophrenic disorder, anorexia, abdominal discomfort, nausea and vomiting, mild fever, and excessive sweating. The use of Beta-carotene should be avoided when this condition exists because exacerbation of symptoms and further vitamin A toxicity will occur.
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