Arginine

Arginine is amino acid produced by the hydrolysis or digestion of proteins. Arginine is one of the hexone bases and supplies the amidine group for the synthesis of creatine. Arginine is also formed by the transfer of nitrogen atom from aspartate to citrulline in the urea cycle. Arginine is effective in the treatment of liver coma and as a stimulant to the pituitary for the release of human growth hormone.


Adult Dose
Dose: 250 to 500 mg/ kg
Single Dose: 380 (375)
Frequency: As recommended.
Route: IV Inf
Instructions: Doses vary according to indications.
Neonatal
Paedriatic
Characteristics
monoglutamate is the derivative of Arginine. It is of Natural and Synthetic origin and belongs to Amino acids. . The Molecular Weight of Arginine is 174.20.
Contraindications
Arginine is contraindicated in conditions like Allergy,Anuria.
Effects
The severe or irreversible adverse effects of Arginine, which give rise to further complications include Thrombocytopenia.The symptomatic adverse reactions produced by Arginine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Inflammation, Headache, Flushing, Nausea and vomiting, Local irritation.
Indications
Arginine is primarily indicated in conditions like Acromegaly, Metabolic alkalosis, and can also be given in adjunctive therapy as an alternative drug of choice in Hypertension.
Interactions
No data regarding the interactions of Arginine was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Injection Protect from Sunlight.
Warnings
Use with caution in patients with history of kidney, liver or stomach problems. Use with caution during pregnancy or lactation.
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