Oxtriphylline (Choline Theophyllinate)

Oxtriphylline (Choline Theophyllinate) is a choline salt of theophylline. It contains 64% theophylline by weight. Oxtriphylline (Choline Theophyllinate) is more soluble and more stable, better absorbed from gastro-intestinal, causes less gastric irritation. Hence, Oxtriphylline (Choline Theophyllinate) is effective orally in the management of acute bronchial asthma and for reversible bronchospasm. Development of tolerance is infrequent; therefore Oxtriphylline (Choline Theophyllinate) is useful for long-term therapy.


Adult Dose
Dose: 800 mg/day
Single Dose: 800 (800)
Frequency: As recommended.
Route: PO
Instructions: Should be taken in 4 divided doses.
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin. . The Molecular Weight of Oxtriphylline (Choline Theophyllinate) is 283.33. It is weakly alkaline drug.
Contraindications
Oxtriphylline (Choline Theophyllinate) is contraindicated in conditions like Peptic ulcer,Gastritis,Hypersensitivity to the drug.
Effects
The severe or irreversible adverse effects of Oxtriphylline (Choline Theophyllinate), which give rise to further complications include Palpitation, Tremors, CNS stimulation.The signs and symptoms that are produced after the acute overdosage of Oxtriphylline (Choline Theophyllinate) include Hypotension, Vomiting, Tachycardia, Convulsions, Dehydration, Diuresis, Metabolic acidosis, Electrolyte disturbances, Agitation.The symptomatic adverse reactions produced by Oxtriphylline (Choline Theophyllinate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Diarrhea, Anxiety, Restlessness, Insomnia, Abdominal pain, Nausea and vomiting, Bleeding.
Indications
Oxtriphylline (Choline Theophyllinate) is primarily indicated in conditions like Asthma, Bronchitis, Bronchospasm, Emphysema.
Interactions
No data regarding the interactions of Oxtriphylline (Choline Theophyllinate) was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Syrup Store Below 40°C. Do not Freeze. Protect from Sunlight and Moisture. Tab Store Below 40°C. Protect from Sunlight and Moisture.
Warnings
Oxtriphylline should be used with caution in patients with severe cardiac, kidney or liver disease, hyperthyroidism, congestive heart failure (CHF), peptic ulcer. It should be used with caution in neonates & elderly persons.
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