Papain

Papain is enzyme of the hydrolase class that catalyzes the hydrolysis of proteins and peptides. The enzyme is obtained from the latex of the papaya, Carica papaya. It has anti-inflammatory properties and effective in relieving symptoms of episiotomy.


Adult Dose
Dose: 1500 mg/day
Single Dose: 1500 (1500)
Frequency: As recommended.
Route: PO
Instructions:
Neonatal
Paedriatic
Characteristics
. It is of Natural origin and belongs to Enzyme. . It is weakly acidic drug.
Contraindications
Papain is contraindicated in conditions like Hypersensitivity to the drug.
Effects
The severe or irreversible adverse effects of Papain, which give rise to further complications include Angioedema.The symptomatic adverse reactions produced by Papain are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Abdominal cramps, Hypersensitivity, Hypernatremia, Arthiritis.
Indications
Papain is primarily indicated in conditions like Constipation, Indigestion, Pain and inflammation.
Interactions
No data regarding the interactions of Papain was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj Store in refrigerator.
Warnings
Papain should be used with caution in patients with any pre-existing illness or any allergy especially to papaya or papain. It should be used only if clearly needed during pregnancy.
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