Calcium Carbonate

Calcium Carbonate occuring naturally in bones, shells etc. Calcium Carbonate is used mainly as an antacid. Calcium Carbonate is used to relieve heartburn by stomach acidity. Calcium Carbonate is most commonly used as a calcium supplement.


Adult Dose
Dose: 540 to 1500 mg
Single Dose: 1000 (1020)
Frequency: 24 hourly
Route: PO
Instructions: In divided doses
Neonatal
Dose: 33.75 to 125 mg/kg
Single Dose: 79 (79.375)
Frequency: 24 hourly
Route: oral
Instructions:
Paedriatic
Dose: 27 to 100 mg/kg
Single Dose: 64 (63.5)
Frequency: 24 hourly
Route: Oral
Instructions: -
Characteristics
. It is of Synthetic origin and belongs to Calcium salt. It belongs to Antacids pharmacological group.The Molecular Weight of Calcium Carbonate is 100.00.
Contraindications
Calcium Carbonate is contraindicated in conditions like Hypercalcaemia,Hyperthyroidism,Hypercalciuria,Nephrolithiasis,Zollinger-ellison syndrome.
Effects
The severe or irreversible adverse effects of Calcium Carbonate, which give rise to further complications include Hypercalciuria, hypercalcemia with alkalosis.Calcium Carbonate produces potentially life-threatening effects which include Hypercalcemia, Renal failure. which are responsible for the discontinuation of Calcium Carbonate therapy.The symptomatic adverse reactions produced by Calcium Carbonate are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Dizziness, Headache, Nausea, Vomiting, Constipation, Abdominal pain, Acid rebound, Belching.
Indications
Calcium Carbonate is primarily indicated in conditions like Flatulence, Heart burn, Hypocalcaemia, Peptic ulcer, Upset stomach, and can also be given in adjunctive therapy as an alternative drug of choice in Hyperphosphataemia, Renal failure.
Interactions
Calcium Carbonate is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCiprofloxacinbinds with drugs or increase pH that effects drug solubilityantacid should not be given within two hours of the dose of these drugsDigoxinCalcium Carbonate may enhance the arrhythmogenic effect of Digoxin.ModerateMonitor toxic effects of digoxin (especially cardiac arrhythmias) if a calcium product (especially I.V.) is initiated or the dose is increased.Iron Saltsbinds with drugs or increase pH that effects drug solubilityantacid should not be given within two hours of the dose of these drugsItraconazolebinds with drugs or increase pH that effects drug solubilityantacid should not be given within two hours of the dose of these drugsSodium Polystyrene SulphonateStrontium-89 ChlorideSaturation of bone-binding sites by calcium may reduce uptake of strontium-89 chloride. ModerateCalcium-containing preparations should be withheld for 2 weeks before until 2 weeks after administration of strontium-89 chloride.Tetracycline (HCl)binds with drugs or increase pH that effects drug solubilityantacid should not be given within two hours of the dose of these drugs These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store Between 20°C-25°C. Protect from Sunlight and Moisture.
Warnings
Calcium carbonate should be used with caution in patients with kidney disease or any allergy, pre-existing cardiac arrhythmias, diarrhoea, malabsorption or diseases associated with elevated vitamin D concentrations such as sarcoidosis. Avoid taking more doses than recommended. Generally calcium salts should be avoided in patients with calcium renal calculi. Plasma-calcium concentrations should be monitored closely in patients with renal insufficiency and during parentral administration and if large doses of vitamin D are used.
Back to List

Any information that appears on this website page is provided for the purpose of general information. This website has been compiled in good faith by HMIS.Online. However, no guarantee is made as to the completeness, validity or accuracy of the information it contains.