Azelastine (HCl)

Azelastine (HCl) is antihistamine. Histamine mediate allergic and inflammatory reactions. Azelastine (HCl) is used to relieve symptoms related to allergic rhinitis. Antihistamine nasal spray is used for symtomatic relief of allergic rhinitis. By this route drug does not cause sedation although nasal irritation and taste dsturbance may occur.

Brands
AZOSIN
Adult Dose
Dose: 0.10%
Single Dose: 0.1 (0.1)
Frequency: 12 hourly
Route: Intra Nasal
Instructions: For each nostril, As Required
Neonatal
Dose: Not recomended in his age group
Single Dose:
Frequency:
Route:
Instructions:
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
. It is of Synthetic origin and belongs to Chlorophenyl Phthalazinone. . The Molecular Weight of Azelastine (HCl) is 418.40. Its pKa is 9.5.
Contraindications
Azelastine (HCl) is contraindicated in conditions like Hypersensitivity.
Effects
The severe or irreversible adverse effects of Azelastine (HCl), which give rise to further complications include Drowsiness.The signs and symptoms that are produced after the acute overdosage of Azelastine (HCl) include Convulsions, Drowsiness, Excitation.The symptomatic adverse reactions produced by Azelastine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Tiredness, Drowsiness, Anorexia, Abdominal pain, Skin rashes, Dry mouth.
Indications
Azelastine (HCl) is primarily indicated in conditions like Allergic rhinitis, Asthma, Bronchitis, and can also be given in adjunctive therapy as an alternative drug of choice in Allergy.
Interactions
No data regarding the interactions of Azelastine (HCl) was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Aerosol Store Between 20°C-25°C. Do not Freeze. Protect from Sunlight and Moisture.
Warnings
Azelastine should be used with caution in patients with kidney, heart or liver disease, any allergy or high blood pressure. This medication should be used only when clearly needed during pregnancy or lactation.
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