LESCOL LESCOL LESCOL XL

Dose: 20 to 40 mg
Single Dose: 30 (30)
Frequency: 24 hourly
Route: PO
Instructions: Should be taken in evening, Daily regimen 80mg/day should be administered in divided doses.

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group

Fluvastatin Sodium is the derivative of Fluvastatin. It is of Synthetic origin and belongs to Statin Derivative. It belongs to HMGCoA reductase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antilipemic Agent pharmacological group.The Molecular Weight of Fluvastatin is 433.50.

Fluvastatin is contraindicated in conditions like Liver diseases,Hepatic dysfunction.

The severe or irreversible adverse effects of Fluvastatin, which give rise to further complications include Angioedema, Myopathy, Rhabdomyolysis, Anaphylaxis.The signs and symptoms that are produced after the acute overdosage of Fluvastatin include Hepatitis, Pancreatitis.The symptomatic adverse reactions produced by Fluvastatin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Myalgia, Dyspnea, Insomnia, Abdominal pain, Blurred vision, Skin rash, Dyspepsia, Elevation of liver enzymes, Nausea and vomiting, Myopathy.

Fluvastatin is primarily indicated in conditions like Acute heart failure, Atherosclerosis, Chronic heart failure, Hypercholesterolaemia, Hyperlipidaemias, Hyperlipoproteinaemia.

Fluvastatin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementBezafibrateIncreased risk of myopathy when fibrates (e.g Bezafibrate) given with statins (e.g Fluvastatin).CholestyramineNicotinic AcidRepaglinideFluvastatin may increase repaglinide concentrations by decreasing metabolism. Warfarin (Na)Fluvastatin may enhance the anticoagulant effect of Warfarin. Moderate (Sequence important)Monitor for increased effects of Warfarin if Fluvastatin is initiated/dose increased, or decreased effects if Fluvastatin is discontinued/dose decreased. Dosage adjustments of Warfarin may be needed. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Caps Store in a well closed container, at room temperature, Below 30°C. Protect from Sunlight and Heat.

Fluvastatin should be used with caution in patients with liver disease, severe infection, kidney disease, heart disease, hypothyroidism or any allergies. Heavy drinking of alcohol can increase blood levels of fluvastatin, do not drink heavily while taking fluvastatin. Fluvastatin should not be used during pregnancy or lactation. It should be discontinued if there is marked increase in serum aminotransferases.