Calciferol

'Calciferol is a vitamin D, a fat soluble sterol, sometimes considered to be hormone or hormone precursor. Calciferol is involved in promoting normal bone development in body by regulating calcium, phosphorus and minerals. Vitamin D is a secosteroid and sometimes popularly known as the ''sunshine vitamin'' because formed in the skin from 7-dehydrocholesterol under the influence of ultraviolet irradiation. Calciferol is also found in certain food. Fish liver oils, especially code liver oil are good sources of vitamin D.'


Adult Dose
Dose: 1.4 ug/ kg
Single Dose: 1.4 (1.4)
Frequency: 24 hourly
Route: PO
Instructions:
Neonatal
Dose: 187.5 units/kg
Single Dose: 190 (187.5)
Frequency: 24 hourly
Route: oral
Instructions:
Paedriatic
Dose: 150 IU/kg
Single Dose: 150 (150)
Frequency: 24 hourly
Route: Oral
Instructions: For Treatment
Characteristics
Calciferol also known as Viosterol, Viosterol, Viosterol, Viosterol, Viosterol. . It is of Natural origin and belongs to Vitamin D. It belongs to Vitamin D agonist pharmacological group on the basis of mechanism of action. The Molecular Weight of Calciferol is 396.70.
Contraindications
Calciferol is contraindicated in conditions like Hypercalcaemia.
Effects
The severe or irreversible adverse effects of Calciferol, which give rise to further complications include Cardiac arrhythmias, Cardiac arrhythmias, Paralytic ileus, Thirst, Dehydration, Polyuria, Nocturia, Abdominal pain, Overt psychosis, Metastatic calcification, Hyperphosphatemia, Hypervitaminosis D.Calciferol produces potentially life-threatening effects which include Cardiac arrhythmias, Renal failure. which are responsible for the discontinuation of Calciferol therapy.The symptomatic adverse reactions produced by Calciferol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Headache, Nausea, Vomiting, Anorexia, Apathy, Somnolence, Weakness.
Indications
Calciferol is primarily indicated in conditions like Hypocalcaemia of hypoparathyroidism, Hypoparathyroidism, Hypophosphataemia, Osteomalacia, Osteoporosis, Prevention of vitamin d deficiency, Renal osteodystrophy, Simple vitamin d deficiency, Vitamin D deficiency, Vitamin D deficiency rickets, and can also be given in adjunctive therapy as an alternative drug of choice in Malabsorption, Post gastrectomy vit B-12 deficiency, Renal diseases.
Interactions
Calciferol is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCalciumCalcium GluconateCholestyramineEstrogens ConjugatedHydrochlorothiazideIsoniazidPhenobarbital SodiumPhenytoin (Na)Verapamil (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Zlatkis-Zac reaction used in the measurement of serum cholesterol concentrations
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store in a well closed container, Below 40°C. Protect from Sunlight.
Warnings
Evaluate Vitamin D administration in fortified food, diet and drugs. It may be necessary to limit dietary Vitamin D during treatment. If products of Vitamin D contain tartrazine may cause allergic reaction (including bronchial asthma) in susceptible individuals, Specially patients with aspirin hypersensitivity.Take care to ensure correct dose infants,monitor plasma calcium concentration in patient receiving high dose and in renal impairment.
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