Lercanidipine (HCl)

Lercanidipine (HCl) is a long acting calcium channel antagonistwith actions similar to Nifedipine. Used as a once-daily treatment for hypertension.it exerts its antihypertensive effect by inhibiting the influx of extracellular calcium across the cell membranes of myocardial and vascular smooth muscle. Serum calcium levels remain unchanged.

Brands
LERADIP ZANIDIP ZANIDIP
Adult Dose
Dose: 10 to 20 mg
Single Dose: 15 (15)
Frequency: 24 hourly
Route: PO
Instructions:
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
belongs to Dihydropyridine. It belongs to Calcium L-channel antagonist pharmacological group on the basis of mechanism of action. The Molecular Weight of Lercanidipine (HCl) is 648.20.
Contraindications
Lercanidipine (HCl)
Effects
The symptomatic adverse reactions produced by Lercanidipine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Fatigue, Nausea, Vomiting, Diarrhea, Palpitation, Tachycardia, Peripheral edema, Hypotension, Flushing, Asthenia, Epigastric pain, GI disturbance, dizziness.
Indications
Lercanidipine (HCl) is primarily indicated in conditions like Hypertension, Mild to moderate hypertension.
Interactions
No data regarding the interactions of Lercanidipine (HCl) was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Lercandipine should be used with caution in pts.with kidney or liver disease.Consider decrease in dose of calcium channel blockers & monitor drug response in cirrhosis pts.
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