Imidapril

Imidapril is a long acting ACE inhibitor. It prevents the conversion of certain enzymes in the body and prevents constriction of blood vessels. It decreases the blood pressure and makes the heart beat stronger. Imidapril is used to treat hypertension (high blood pressure) and heart failure.

Brands
TANATRIL TANATRIL
Adult Dose
Dose: 5 to 10 mg
Single Dose: 7.5 (7.5)
Frequency: 24 hourly
Route: PO
Instructions: Max. 20 mg once daily.
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
belongs to Imidazoline. It belongs to Angiotensin converting enzyme inhibitor-ACEI pharmacological group on the basis of mechanism of action and also classified in Antihypertensive Agents pharmacological group.The Molecular Weight of Imidapril is 405.40.
Contraindications
Imidapril is contraindicated in conditions like Angioedema.
Effects
The severe or irreversible adverse effects of Imidapril, which give rise to further complications include Increased BUN (blood urea nitrates), Increased creatinine.The symptomatic adverse reactions produced by Imidapril are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Palpitation, Abdominal pain, Cough, Nausea and vomiting, Decrease in hemoglobin, Decrease in hematocrit, Albuminuria, dizziness.
Indications
Imidapril is primarily indicated in conditions like Essential hypertension, Hypertension.
Interactions
Imidapril is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementLithiumNitroglycerinRifampicinRifampicin reduces plasma concentration of active metabolite of Imidapril (reduced antihypertensive effect)Spironolactone These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store Below 40°C.
Warnings
Imidapril Hcl may produce dizziness or light-headedness due to hypotension. Use caution when driving, operating machinery or performing other tasks requiring mental alertness. Administration is not recommended within 24 hours prior to surgery.
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