Hydroxyethyl Starch

Hydroxyethyl Starch is a starch that is composed of more than 90 % of amylopectin. Hydroxyethyl Starch is a plasma voluma expander. Hydroxyethyl Starch is used in the managemnt of hypovolumic shock.


Adult Dose
Dose: 33 to 66 ml/ kg
Single Dose: 50 (49.5)
Frequency: As recommended.
Route: IV Inf
Instructions: As Required
Neonatal
Paedriatic
Dose: Safety and efficacy have not been established.
Single Dose:
Frequency:
Route:
Instructions:
Characteristics
belongs to Amylopectin. It belongs to Plasma Protein Fractions pharmacological group.The Molecular Weight of Hydroxyethyl Starch is 50000.00.
Contraindications
Hydroxyethyl Starch is contraindicated in conditions like Renal failure,Haemorrhage,Anuria,Oliguria,Coagulation disorder.
Effects
The severe or irreversible adverse effects of Hydroxyethyl Starch, which give rise to further complications include Increased serum amylase.Hydroxyethyl Starch produces potentially life-threatening effects which include Anaphylaxis. which are responsible for the discontinuation of Hydroxyethyl Starch therapy.The symptomatic adverse reactions produced by Hydroxyethyl Starch are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Tachycardia, Itching, Fall in BP.
Indications
Hydroxyethyl Starch is primarily indicated in conditions like Burns, Hypovolaemia, Infections, Low blood volume, Shock, Trauma.
Interactions
No data regarding the interactions of Hydroxyethyl Starch was found.
Interfrence
Increases Serum Bilirubin
Risks
Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Caution should be observed before administering Hydroxyethyl Starch to patients with severe liver disease or severe bleeding disorders. In cases of severe dehydration, a crystalloid solution should be given first. Generally, sufficient fluid should be administered in order to avoid dehydration.
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