RGESIC EXTRA RGESIC EXTRA TYLADOL EXTRA PABFIN EMPIRIN COMP MIGRIL IODOPYRIN ASMOL ORPHAGESIC CAFERGOT OPTALIDON OPTALIDON TONUM TONUM VIGROL FORTE DONAMOL PLUS DONAMOL PLUS DONAMOL PLUS DONAMOL PLUS SARIDON C.C DON EXTRA PARA+PLUS PARA+PLUS PARACETAMOL COMPOUND TRIGESIC ZEPYRINE VASOLOID PARACETAMOL COMPOUND PARACETAMOL COMPOUND FERROGLOBIN FERROGLOBIN CAFFEINE CITRATE AMADOL EXTRA AMADOL EXTRA ESTADOL EXTRA TYLOL EXTRA VIKONON FORTE AMSIDAL SCHAZOPYRIN PANARIN DELMOL EXTRA DIAGESIC-P BARIDON CAFIPAR CANIDOL CANIDOL BARBIDOL PAROL PLUS AMTALIDIN SUMMERVITA SUMMERVITA AMOLE PLUS PARAHEIM PLUS PARAHEIM PLUS PARAHEIM PLUS PAXFIN RESIDOL EXTRA CALPOL PLUS PANADOL EXTRA MEDIGESIC C MEDIGESIC C PEDROL EXTRA FEBROL XTRA NAPADOC JUVAPYRINE PARATOL EXTRA KAPRIN COMPOUND KAPRIN COMPOUND PANAFIN EXTRA MEDINOL TERINOL FEDRAMOL PLUS NUBEROL PLUS EROPYRIN EROPYRIN ASCAMOL ASCAMOL FEVAMOL EXTRA RASCODOL PLUS RASCODOL PLUS NOPAIN NOPAIN AF PAMOL X TAGRIL ADALGIN APECIRIN EXCEDRIN-XTRA ASPIRIN COMP ASPIRIN COMP DETAMOL EXTRA SYNADOC SYNADOC MB-FORTE MB-FORTE MB-TONE FORTE FEBRICOD C TEMPOL-C IRZAPOLE PLUS JETAMOL EXTRA PYRECAF PLUS CURIDOL EXTRA ARIDOL AMSIPOL MEDIGESIC FORTE MEDIGESIC FORTE MEDIGESIC FORTE EFRODOL OMNIDOL DANCIN DANCIN NEDOL EXTRA AXADOL PLUS DOLMI PARA-CAFFIN PYROL EXTRA REGODOL EXTRA REGODOL PLUS AMIDOL AMIDOL FEVERAMIN-D PREGESIC ROVIDOL AZIDOL CAYDOL EXTRA CAYDOL EXTRA CHILPOL EXTRA PARARI XTRA FEMIDOL PLUS FENMOL EXTRA TRIGIN VIOZONE WYLADOL EXTRA ACTIRON CF FANIDOL PANGESIC+C PARAD EXTRA ROMTOLIDO TYLENOL EXTRA VIDOL-EXTRA PARAGRAY EXTRA PRYMIN DEE DISOL FENMOL PLUS

Dose: 100 to 200 mg
Single Dose: 150 (150)
Frequency: As recommended.
Route: PO,IV
Instructions:

Dose: 2.5
Single Dose: 2.5 (2.5)
Frequency: As recommended.
Route: Intravenous
Instructions: Maintenance

Dose: 2.5
Single Dose: 2.5 (2.5)
Frequency: As recommended.
Route: Intravenous
Instructions: Maintenance

Caffeine also known as Methyl Theobromine, Methyl Theobromine, Methyl Theobromine. . It is of Natural origin and belongs to Xanthine. It belongs to Phosphodiesterase inhibitor pharmacological group on the basis of mechanism of action and also classified in CNS Stimulant pharmacological group.The Molecular Weight of Caffeine is 194.20. Its pKa is 13.9.

Caffeine is contraindicated in conditions like Cardiac arrhythmia,Peptic ulcer.

The severe or irreversible adverse effects of Caffeine, which give rise to further complications include Tachycardia, Caffeinism, Irregular fever, Insomnia, Anorexia, Anxiety, Irritability, CNS stimulation, Diuresis, Tachycardia.Caffeine produces potentially life-threatening effects which include Tinnitus, Nausea, Vomiting, Tachycardia, Hypersensitivity, Restlessness, Agitation, Anxiety, Diuresis, Palpitation, Shock, Urticaria, Hyperglycemia. which are responsible for the discontinuation of Caffeine therapy.The signs and symptoms that are produced after the acute overdosage of Caffeine include Tachycardia, Emesis, Diuresis, CNS stimulation, Metabolic acidosis, Ketosis, Hyperglycemia, Acetonuria.The symptomatic adverse reactions produced by Caffeine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Irritability, Nausea, Vomiting, Anorexia, Anxiety, Restlessness, Tremors, Insomnia, Epigastric pain.

Caffeine is primarily indicated in conditions like Apnoea of prematurity, CNS stimulation, Headache, Migraine, and can also be given in adjunctive therapy as an alternative drug of choice in Asthma, Lumbar puncture headache.

Caffeine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlcoholCimetidine (HCl)CinoxacinCiprofloxacinCoadministration inhibit the metabolism of caffeine thus increasing its plasma concentration and pharmacological effect.Ciprofloxacin increases caffeine AUC by 50% to over 100% and reduces its clearance upto 50%.ModerateCaffeine intake should be avoided during treatment that may increase the risk of adverse effects like tremor,insomnia,tachycardia and blood pressure.DiazepamDipyridamoleDisulfiramDue to inhibition of caffeine metabolism in liver microsomes its concentration may be increases in cardiovascular and CNS .MinorCaffeine intake should be limited while taking disulfiram.EnoxacinFenoterol Use of Fenoterol with caffeine may increase risk of hypokalemia. Frusemide or FurosemideIron SaltsLevonorgestrelMexiletineNimodipineNorfloxacinPentobarbitone (Na)Phenytoin (Na)Pipemidic AcidRiluzoleCaffeine could decrease the rate of riluzole elimination. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Determ. of Uric Acid Conc. in bio. fluids by colorimetric method utilizing phosphotungistic acid.

Drug should not be given to patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store at room temperature. Protect from Sunlight, Moisture and Heat.

Caffeine should be used with caution in diabetic patients because it may produced hyperglycemia, in anxiety disorder or panic disorder because it can aggrevate these conditions, in hepatic disease or hepatic impairment and during pregnancy and breast feeding.