Glycerin

Glycerin is a clear, syrupy liquid obtained as a by-product of soap, by carbohydrate fermentation and by propylene synthesis. Glycerin is administered rectally and orally. Glycerin is used topically for its softening and water retaining properties and also in constipation as a stool softener.


Adult Dose
Dose: 500 mg
Single Dose: 500 (500)
Frequency: 24 hourly
Route: PO
Instructions: Maintenance, As Required
Neonatal
Paedriatic
Characteristics
belongs to Propanetriol. It belongs to Diuretics and Emollient pharmacological group.The Molecular Weight of Glycerin is 92.09. It is weakly acidic drug, 2.60% solution of the drug is isotonic.
Contraindications
Glycerin is contraindicated in conditions like Nausea and vomiting,Anuria,Intestinal obstruction,Pulmonary edema.
Effects
The symptomatic adverse reactions produced by Glycerin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Weakness, Dizziness, Thirst, Headache, Diarrhea, Abdominal cramps, Irregular heart beat, Confusion, Nausea and vomiting, Fall in BP, Bloating, Ocular irritation and pain, Confusion, dizziness, Weakness, Severe Dehydration.
Indications
Glycerin is primarily indicated in conditions like Constipation, Dry skin, Skin diseases, Sore throat.
Interactions
Glycerin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementFloxacillin (Na)Tincture MyrrhTincture Myrrh may increase the level of suger in blood if taking myrrh by mouth & may interfere with the effectiveness of medications used for the treatment of diabetes. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
None well documented
Risks
Drug should not be given to Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Liq Store Below 40°C. Protect from Sunlight and Moisture. Suppositories Store Below 25°C. Protect from Sunlight and Moisture.
Warnings
Glycerine should be used with caution in patients of hypervolemia, confused mental state, congestive heart disease, diabetic patients and dehydrated individuals, Pregnancy.
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