Fosfomycin

Fosfomycin is analog of phosphoenolpyruvate. Fosfomycin is structurally unrelated to any other antimicrobial agent. Fosfomycin is active against both gram negative and gram positive bacteria. It has been used successfully in the treatment of pneumonia, UTIs, bronchitis, and other respiratory tract infections. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular interval of time throughout the day and night as prescribed. Fosfomycin is important to take the drug for the full time period as prescribed. If you discontinue the drug it may result in ineffective treatment.

Brands

FOSOMIN FOSOMIN FOSOMIN FOSOMIN FASFOCIN FOSFOMYCIN MONUROL FOCIN FOCIN FOCIN FOCIN FOCIN FOSFOMYCIN FOSFOMYCIN FOSFOMYCIN FOSFOMYCIN SPAIN FOSFOMYCIN SPAIN FOSFOMYCIN SPAIN FOSFOMYCIN SPAIN MIFOS SONOMYCIN FOSFIN FOSFIN FACTUM FACTUM FOSFORIN FOSFORIN EFOMYCIN EFOMYCIN FOSFOMYCIN CHINA FOSFOMYCIN CHINA FOSFOMYCIN CHINA FOSFOMYCIN CHINA FOSORIL FOFY TRIFOCIN FOSFOMYCIN FOSFOSAF FOSME FOSME FISMIN FOMOCIN FOSAV FOSAV DS FOSFOMYCIN FOSFOMYCIN FOSFOMYCIN FOSFOMYCIN OB-FOSFO-5 Fosival

Adult Dose

Dose: 1 g
Single Dose: 1 (1)
Frequency: 8 hourly
Route: IM
Instructions:

Neonatal

Dose: 31.25 mg/kg
Single Dose: 31 (31.25)
Frequency: 12 hourly
Route: Intramuscular
Instructions:

Paedriatic

Dose: 50 mg/kg
Single Dose: 50 (50)
Frequency: 8 hourly
Route: Intra Muscular
Instructions: -

Characteristics

Fosfomycin Calcium is the derivative of Fosfomycin. It is of Semi Synthetic origin and belongs to Phosphoric Acid. It belongs to Antibiotic (Cell Wall) pharmacological group on the basis of mechanism of action. The Molecular Weight of Fosfomycin is 138.10.

Contraindications

Fosfomycin is contraindicated in conditions like Hypersensitivity to the drug.

Effects

The symptomatic adverse reactions produced by Fosfomycin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Diarrhea, Vaginitis, Asthenia, Increased intracranial pressure.

Indications

Fosfomycin is primarily indicated in conditions like Urinary tract infection.

Interactions

Fosfomycin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCefotaximesynergestic effect aganist methicillin resistant staphylococci.Metoclopramide (HCl) These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Interfrence

Risks

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Storage

Powder Store in a well closed container, Below 40°C. Protect from Sunlight and Moisture.

Warnings

Fosfomycin should be used with caution in patients with medical history, including any allergy, especially drug allergy or kidney disease. It should be used with caution during pregnancy and not recommended during lactation. Caution is advised for use in females under 18 years old.

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