Formestane

Formestane used in the treatment of advanced estrogen dependent breast cancer.


Brands
Adult Dose
Dose: 3.571 mg/kg
Single Dose: 3.6 (3.571)
Frequency: As recommended.
Route: IM
Instructions: Fortnightly
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
belongs to Androstenedione. It belongs to Antineoplastic Agent, Aromatase Inhibitor pharmacological group.The Molecular Weight of Formestane is 302.40.
Contraindications
Formestane is contraindicated in conditions like Premenopausal breast cancer.
Effects
The severe or irreversible adverse effects of Formestane, which give rise to further complications include Vaginal bleeding.Formestane produces potentially life-threatening effects which include Anaphylaxis. which are responsible for the discontinuation of Formestane therapy.The symptomatic adverse reactions produced by Formestane are more or less tolerable and if they become severe, they can be treated symptomatically, these include Skin reactions, Bone pain, Arthralgia, Muscle cramps, Hot flushes.
Indications
Formestane is primarily indicated in conditions like Breast cancer.
Interactions
No data regarding the interactions of Formestane was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj (reconstituted susp) Store in refrigerator. Use within 24 hrs if kept at room temperature. Vial Store at room temperature.
Warnings
Formestane is not recommended for use during pregnancy or lactation. Immunosuppressent drug should not be given, where possible, to patients with acute infection, dosage reduction or withdrawal should be considered if infection develops, until the infection has been controlled. Blood counts and measurement of hemoglobin concentration should be carried out routinely, it helps to predict the onset of bone marrow depression. It must be handled with great care and avoid contact with skin and eyes, and should not be inhaled.
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