Flavoxate (HCl)

Flavoxate (HCl) is antispasmodic agent. It relaxes the muscles of the urinary tract. Flavoxate (HCl) is used to relieve pain, burning, urinary urgency and frequency associated with urinary tract, bladder and prostate infections.


Adult Dose
Dose: 100 to 200 mg
Single Dose: 150 (150)
Frequency: 8 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
belongs to Piperidine. It belongs to Cholinergic muscarinic antagonist pharmacological group on the basis of mechanism of action and also classified in Antidotes and Antispasmodic Agent, Urinary pharmacological group.The Molecular Weight of Flavoxate (HCl) is 427.90. It is weakly acidic drug and Its pKa is 7.3.
Contraindications
Flavoxate (HCl) is contraindicated in conditions like GI ulceration,Pyloric disease,Obstructive uropathy,GI obstruction.
Effects
The severe or irreversible adverse effects of Flavoxate (HCl), which give rise to further complications include Eosinophilia, Eosinophilia, Leucopenia.Flavoxate (HCl) produces potentially life-threatening effects which include Hyperkalemia, Toxic Megacelon, Gastrointestinal hypomotility, Anaphylaxis, Hyperkalemia, Malignant hyperthermia. which are responsible for the discontinuation of Flavoxate (HCl) therapy.The symptomatic adverse reactions produced by Flavoxate (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Drowsiness, Fever, Palpitation, Tachycardia, Constipation, Nervousness, VertigoX, Nausea and vomiting, Xerostomia, nervousness, Nervousness, Increased intraocular pressure.
Indications
Flavoxate (HCl) is primarily indicated in conditions like Bladder spasm due to catheterization, Dysuria, Fatigue, Nocturia, Pain, Prostatitis, Sedation, Spasticity, Urethritis, Urethrocystitis, Urethrotrigonitis, Urgency and incontinence.
Interactions
No data regarding the interactions of Flavoxate (HCl) was found.
Interfrence
Interference in UrinationComplications in bladerInterference with the tubulin microtubule equilibiriumInterference in the Protein folding w/c occurs in the synthesis of melonin
Risks
Drug should not be given to Paediatrics, Pregnant Mothers, Cardiac / Hypertensive Patients, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store in a well closed container, Below 40°C. Protect from Sunlight and Heat.
Warnings
Flavoxate should be used only if clearly needed during pregnancy. It should be used with caution in patients with any pre-existing kidney disease, stomach or intestinal disorders or glucoma or if have any allergy.
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