Fexofenadine

Fexofenadine (HCl) is antihistaminic agent. Histamine mediates allergic and inflammatory reactions. Fexofenadine (HCl) is used to relieve allergy symptoms such as watery, itchy, red eyes, sneezing, runny nose etc.


Brands
TELFAST TELFAST TELFAST TELFAST-D TALERGIN-F FEXET FEXET FEXET FEXET FEXET FEXINOL FEXINOL FEXINOL FENADEX FENADEX FENADEX FEXO FEXO FEXO FEXO FEXO-D ALRIN ALRIN ALRIN NOVAHIST NOVAHIST MEGAFAST MEGAFAST MEGAFAST PLEXID PLEXID PLEXID EXO ALLERGIA ALOC ALOC ALOC FAXODINE FAXODINE FAXODINE XADINE XADINE XADINE MEADOW MEADOW MEADOW FANAMED FENDINA FENDINA FENDINA FENIX FENIX FENIX TILAST OFENAD FEXOKURE FEXOKURE FEXOKURE FEXERA FEXERA FEXOLYD FEXOLYD FIXFAST FIXFAST FIXFAST KOVENCE KOVENCE SB-DIN SIZZLE SIZZLE SIZZLE SNEEZ SNEEZ SNEEZ TEFEND TEFEND TEFEND FENADRIN FENADRIN FENADRIN FEKOM FEKOM FEKOM G-FAST FAXHEAL FAXHEAL FAXHEAL FEXOTEL-3H FEXOTEL-3H FENOFEX FENOFEX FENOFEX FENOXY FENOXY FENOXY HASTY HASTY FORT TELFEX TELFEX TELFEX-D FAXAR FEXINE FEXINE REMAST-P FESJET FESJET FEXOSURE FEXIGRA FEXIGRA TANSIDIN UNIFENADINE UNIFENADINE WELFAST WELFAST UFOXIN UFOXIN AXODINE AXODINE AXODINE AXODINE-D FANASEL FANASEL FENADRIN D FEXOTA FEXOTA PLUS FEXET D FIFEX FIFEX FIFEX NEXOFEN NEXOFEN NEXOFEN FEXOFAST FEXOFAST FEXOFAST FEXOFAST FEXOFAST FEXOFAST GERIDIN FIOFEN FIOFEN FIOFEN FENDINA D FANOXIN FANOXIN FEAS FEAS FENADIN FEXICAME FEXICAME FEXOPRIME FEXOPRIME FEXOPRIME GENFIX GENFIX GENFIX HISTAFEX HISTAFEX NIFTY NIFTY XFR XFR XYFEX TELWIN ALLERGOFEX ALLERGOFEX ALLERGOFEX VASOFAX VASOFAX FEXHEAL FEXHEAL SIZZLE D FEXOFIN FEXOFIN FEXOFIN ALOC D FEXOFIN D FASTEC-D ALLER ALLER ALLER FEXOCARE FEXOCARE FEXOCARE FEXOWAN FEXOWAN CIBLER CIBLER CIBLER ELERGIFEN ELERGIFEN ELERGIFEN GENFIX-D MEXODINE MEXODINE REGOFAST REGOFAST REGOFAST REGOFAST D REMAST REMAST REMAST XOFEA XOFEA XOFEA A-DINE AFEX AFEX AFEX ALERFEX ALERGINO ALERGINO ALLERFEDIN ALLERFEDIN ALLERFEDIN ALLERGOFEX PLUS EXIT EXIT EXIT-D FENOSAF FEXASIA PLUS FEXFA FEXODRINE FEXOREX FEXOREX FEXOSNEEZ FEXOSNEEZ HIFEXO SOFTIN-F SOFTIN-F SOFTIN-F XOFENA XOFENA XOFENA ASPEN ASPEN ASPEN EPODIN EPODIN EPODIN FANASEL PLUS FEXOCARE FEXOCARE FEXOCARE FEXOFAX FEXOFAX FEXOFAX NOVAHIST-D NOVAHIST-D TIDIN TIDIN ALLEGRA ADINE ADINE ADINE ALOFEX AXIFAX FEXIGEN FEXIGEN FEXIGEN FEXODERM FEXSEL MAKFEX FENOXIN CF ALZERA EXOFEN EXOFEN FENDIN REVOFEX SAPIFEX FENACARE
Adult Dose
Dose: 120 to 180 mg
Single Dose: 150 (150)
Frequency: 12 hourly
Route: PO
Instructions: should be given in two divided doses._x000D_reduce the dose by half in patients with renal impairment
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
belongs to piperadine. It belongs to H1-antagonist pharmacological group on the basis of mechanism of action. The Molecular Weight of Fexofenadine is 501.66.
Contraindications
Fexofenadine
Effects
The severe or irreversible adverse effects of Fexofenadine, which give rise to further complications include Viral infections.The signs and symptoms that are produced after the acute overdosage of Fexofenadine include Convulsions, Coma, Hallucinations, Ataxia, Cardiorespiratory collapse, Tremor, Ventricular arrhythmias, Cardiovascular collapse, Sedation, Hyperreflexia, Psychosis, Excitement.The symptomatic adverse reactions produced by Fexofenadine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Drowsiness, Nausea, Vomiting, Diarrhea, Tinnitus, Hypotension, Hair loss, Hypersensitivity reactions, Blood dyscrasias, Increased intracranial pressure, Dysmenorrhea, CNS depression, Cold & flu, psychomotor impairment.
Indications
Fexofenadine is primarily indicated in conditions like Allergy, Chronic idiopathic urticaria, Cytotoxic-induced neutropenia, Hay fever, Rhinitis, Seasonal allergic rhinitis, Symptomatic relief of seasonal allergic rhinitis, Urticaria, and can also be given in adjunctive therapy as an alternative drug of choice in Runny nose, Sneezing.
Interactions
Fexofenadine is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementErythromycinerythromycin increase plasma concentration of fexofenadineItraconazoleKetoconazoleKetoconazole increase plasma concentration of fexofenadineQuinineSilymarinSilymarin may interfere with Fexofenadine, because both drugs are broken down by the same liver enzymes.Sotalol (HCl)The Concomitant use of both drugs can lead to QT interval prolongation These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to patients suffering from Kidney dysfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Caps Store in a well closed container, Between 20°C-25°C. Protect from Sunlight and Moisture.
Warnings
Fexofenadine should be used with caution in patients with kidney disease or any allergy, hepatic impairment. Do not take this medication for several days before any allergy testing since test results can be affected. Although drowsiness is uncommon at usual doses under normal circumstances, be aware that this medication may have such effects, before engaging in activities requiring alertness. This medication should be used only if clearly needed during pregnancy or lactation. Caution is advised when this drug is used in the elderly patients.
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