Buserelin (Acetate)

Buserelin (Acetate) is analogue of gonadotrophin-releasing hormone that suppresses androgen production by testes. Buserelin (Acetate) is used in the treatment of carcinoma of prostate and endometriosis.


Brands
Adult Dose
Dose: 100 mcg
Single Dose: 100 (100)
Frequency: 4 hourly
Route: Nasal
Instructions: For 6 Months
Neonatal
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Paedriatic
Dose: Rerely used in this Age Group
Single Dose:
Frequency:
Route:
Instructions:
Characteristics
. It is of Synthetic origin and belongs to Peptide Hormone. . The Molecular Weight of Buserelin (Acetate) is 1239.40.
Contraindications
Buserelin (Acetate)
Effects
The severe or irreversible adverse effects of Buserelin (Acetate), which give rise to further complications include Histological changes in testis.The symptomatic adverse reactions produced by Buserelin (Acetate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Menopausal symptoms, Loss of libido, Hot flushes.
Indications
Buserelin (Acetate) is primarily indicated in conditions like Endometriosis, Fibroids, In-vitro fertilization programmes, Mobilisation of peripheral blood progenitor cells, Pituitary desensitisation, Polycystic ovary syndrome, Precocious puberty, Prostatic cancer, and can also be given in adjunctive therapy as an alternative drug of choice in Advanced prostate cancer.
Interactions
No data regarding the interactions of Buserelin (Acetate) was found.
Interfrence
Risks
Drug should not be given to Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Injection, Nasal Spray Store in a well closed container. Refrigeration is recommended. Protect from Sunlight and Moisture.
Warnings
Buserelin should not generally use in patients with pituitary adenoma. It is also recommended that patients with weight related amenorrhoea should not receive this medication until their weight is corrected. It is not recommended for use during pregnancy.
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