Estazolam

Estazolam used to treat anxiety and sleeping disorders.


Adult Dose
Dose: 1 to 2 mg
Single Dose: 1.5 (1.5)
Frequency: 24 hourly
Route: PO
Instructions: At bedtime.
Neonatal
Paedriatic
Characteristics
. It is of Synthetic origin and belongs to Benzodiazepine. It belongs to Chloride Channel opener (Gaba operated) pharmacological group on the basis of mechanism of action and also classified in Anxiolytics pharmacological group.The Molecular Weight of Estazolam is 294.75.
Contraindications
Estazolam is contraindicated in conditions like Myasthenia gravis.
Effects
The severe or irreversible adverse effects of Estazolam, which give rise to further complications include Dependency.Estazolam produces potentially life-threatening effects which include Central nervous system disorders. which are responsible for the discontinuation of Estazolam therapy.The symptomatic adverse reactions produced by Estazolam are more or less tolerable and if they become severe, they can be treated symptomatically, these include Sleepiness, Vertigo, Headache, Drowsiness, Light-headedness, Confusion, Gait disorder, Confusion, Verligo.
Indications
Estazolam is primarily indicated in conditions like Insomnia.
Interactions
Estazolam is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCarbamazepineIsoniazidPhenobarbitonePhenytoin (Na)RifampicinVORICONAZOLEVoriconazole may increase the serum concentration of estazolam by decreasing its metabolism. Monitor for estazolam toxicity if voriconazole is initiated or dose increased. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Urinanalysis
Risks
Drug should not be given to Paediatrics, and Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tab Store Below 40°C. Protect from Sunlight and Heat.
Warnings
Estazolam should be used with caution in patients with any pre-existing kidney disease, liver disease, history of drug dependence, depression, breathing problems, apnea, seizures or if have any allergies. This medication should not be used during pregnancy or lactation.
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