LIVIAL TIBOPAUSE LOBION-HRT

Dose: 2.5 mg
Single Dose: 2.5 (2.5)
Frequency: 24 hourly
Route: PO
Instructions:

Dose: Not applicable in this age group
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Frequency:
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Dose: Not applicable in paeds
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belongs to Steroid. It belongs to Hormones and Gonadomimetic pharmacological group.The Molecular Weight of Tibolone is 312.40.

Tibolone is contraindicated in conditions like Vaginal bleeding,Liver diseases,Thromboembolism,Cardiovascular disease,Cerebrovascular disease.

The symptomatic adverse reactions produced by Tibolone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Nausea, Abdominal pain, Rashes, Pruritus, Weight gain, Edema, Migraine.

Tibolone is primarily indicated in conditions like Menopausal symptoms, Osteoporosis, Osteoporosis prophylaxis, Sedation with amnesia.

Tibolone is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCarbamazepineCarbamazepine accelerates metabolism of Tibolone (reduced plasma concentration).Phenytoin (Na)Rifampicin These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store at room temperature, Below 25°C or in refrigerator. Do not Freeze. Protect from Sunlight and Moisture.

Tibolone is not recommended for use in women with hormone-dependant tumors, cardiovascular or cerebrovascular disorders, undiagnosed vaginal bleeding or severe liver disorders. It should not be given to pregnant or lactating women and should not be used prior to the menopause because menstrual regularity may be disturbed. Use of tibolone within 12months of a natural menopause is not recommended. It should be used with caution in patients with disorders that may be exacerbated by fluid retention such as kidney dysfunction, epilepsy or migraine, hypercholesterolaemia and impaired glucose tolerance. Discontinue use if there is sign of thrombo-embolism or if abnormal liver function tests or cholestatic jaundice occur.