Tetanus Toxoid

Tetanus Toxoid is a sterile solution of the formaldehyde treated products of growth of Clostridium tetani. It may be used for active immunization to protect against tetanus infection. Tetanus Toxoid is commonly given to all children between two months and six years of age. At the time of injury in older children booster injections may be required and adults if it has been 5-10 years since the last tetanus vaccine was received.


Adult Dose
Dose: 40 IU
Single Dose: 40 (40)
Frequency: As recommended.
Route: IM
Instructions: 2 Inj. at an interval of 4 weeks. 3rd Inj. after 3-12 months, 4th inj. after 1 year and then after 5 years. Booster Dose, Every 10-Years
Neonatal
Paedriatic
Characteristics
It belongs to Vaccines and Toxoids pharmacological group.
Contraindications
Tetanus Toxoid is contraindicated in conditions like Anaphylactic reactions,Hypersensitivity to any component of product.
Effects
The severe or irreversible adverse effects of Tetanus Toxoid, which give rise to further complications include Deaths, Shock.Tetanus Toxoid produces potentially life-threatening effects which include Anaphylactic reactions. which are responsible for the discontinuation of Tetanus Toxoid therapy.The symptomatic adverse reactions produced by Tetanus Toxoid are more or less tolerable and if they become severe, they can be treated symptomatically, these include Urticaria.
Indications
Tetanus Toxoid is primarily indicated in conditions like Tetanus prevention.
Interactions
Tetanus Toxoid is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCimetidine (HCl)Tetanus Immune Globulin (Human)Never administer tetanus toxoid and Tetanus Immune Globulin (Human) in same syringe as toxoid will be neutralized.Toxoid may be given at a separate site. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
SC Inj, IM Inj Store in refrigerator. Do not Freeze.
Warnings
Toxoid should be used only if clearly needed during pregnancy or lactation. It should be used with caution in patients with pre-existing infections, asthma a history of a reaction to a previous vaccination or any allergy, especially to horse serum.
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