Terbinafine (HCl)

Terbinafine (HCl) is antifungal agent. Terbinafine (HCl) is a synthetic allylamine and available as oral and topical formulation. Oral terbinafine is highly effective for treating onychomycosis due to its fungicidal activity and ability to concentrate within the nails.


Adult Dose
Dose: 250 mg
Single Dose: 250 (250)
Frequency: 24 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
. It is of Synthetic origin. It belongs to Antifungal Agent, Oral pharmacological group.
Contraindications
Terbinafine (HCl) is contraindicated in conditions like Hypersensitivity.
Effects
The symptomatic adverse reactions produced by Terbinafine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Anorexia, Abdominal pain, Rashes, Urticaria, Redness, Itching, Increased intracranial pressure, Stinging.
Indications
Terbinafine (HCl) is primarily indicated in conditions like Athelets foot, Dermatophyte infections of the nails, Fungal infection, Hair and nail infection, Iron-deficiency anaemia prophylaxis or for mild iron deficiency, Ringworm, Skin infections, Tinea corporis, Tinea cruris, Tinea pedis, Yeast infection.
Interactions
Terbinafine (HCl) is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementCimetidine (HCl)RifampicinTamsulosin HydrochlorideTamsulosin Hydrochloride should be used with caution in combination with Terbinafine (HCl). These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Abnormal liver enzymes
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Cream Store Below 40°C. Protect from Sunlight and Heat. Tab, Cream Store Between 15°C-25°C. Protect from Sunlight and Heat.
Warnings
Terbinafine should be used only if clearly needed during pregnancy. It should be used with caution in patients with any pre-existing illness, infections or allergy, especially to any antibiotic.
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