Teicoplanin

Teicoplanin is a glycopeptide antibiotic. Teicoplanin is very similar to Vancomycin in mechanism of action and antibacterial spectrum. Teicoplanin is effective against gram positive bacteria. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular intervals of time throughout the day and night as prescribed. Teicoplanin is important to take the drug for the full time period as prescribed. discontinuation of the drug, may result in ineffective treatment.

Brands
TARGOCID TARGOCID TAPOCIN PLANIN TEICON TEICOX TEICOX TEICOX TEICOX
Adult Dose
Dose: 200 mg
Single Dose: 200 (200)
Frequency: 24 hourly
Route: IV,IM
Instructions: Maintenance, on each subsequent day of treatment.
Neonatal
Dose: 6 to 10 mg/kg
Single Dose: 8 (8)
Frequency: 24 hourly
Route: Intra Muscular
Instructions: Maintenance
Paedriatic
Dose: 6 to 10 mg/kg
Single Dose: 8 (8)
Frequency: 24 hourly
Route: Intra Muscular
Instructions: Maintenance
Characteristics
. It is of Semi Synthetic origin and belongs to Glycopeptide. It belongs to Peptidoglycan transpeptidase inhibitor pharmacological group on the basis of mechanism of action.
Contraindications
Teicoplanin is contraindicated in conditions like Epilepsy,Convulsions,Hypersensitivity.
Effects
The severe or irreversible adverse effects of Teicoplanin, which give rise to further complications include Bronchospasm, Ototoxicity, Eosinophilia, Renal failure.The symptomatic adverse reactions produced by Teicoplanin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Fever, Tinnitus, Rashes, GI upset, Hearing loss, Angioedema, Rigors, Reaction at injection site.
Indications
Teicoplanin is primarily indicated in conditions like Bacillary dysentery, Bacterial infections, Constipation, Constipation and bowel evacuation, Endocarditis, Endocarditis treatment, GI infections, Potentially serious gram +ve infections, Respiratory tract infections, Septicaemia, Serious infections due to staphylococcus aureus, Skin infections, Soft tissue infections, Urinary tract infection.
Interactions
No data regarding the interactions of Teicoplanin was found.
Interfrence
Risks
If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Inj Store Below 25°C.
Warnings
Teicoplanin should be used with caution in the patient with hypersentivity to vancomycin, Perform regular hematological, liver, renal and auditory tests. Use with caution during pregnancy and lactation.
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