Sulfanilamide

Sulfanilamide is antibecterial agent. It was one of the first sulphonamides introduced, but noe largely replacced by more effective and safer congeners. Sulfanilamide is not recommendee for systemic therapeutic use. Sulfanilamide is effective for the treatment of certain vaginal infections.

Brands
SULPHAKREAM-N
Adult Dose
Dose: 15%
Single Dose: 15 (15)
Frequency: 12 hourly
Route: Intra Vaginal
Instructions: -
Neonatal
Paedriatic
Characteristics
belongs to Sulphonamide. It belongs to Antibacterial pharmacological group.The Molecular Weight of Sulfanilamide is 172.20. Its pKa is soluble.
Contraindications
Sulfanilamide is contraindicated in conditions like Anaemia,Urinary obstruction,Pregnancy,Hypersensitivity to any component of product.
Effects
The severe or irreversible adverse effects of Sulfanilamide, which give rise to further complications include Stevens johnson syndrome, Urinary tract infection, Porphyria.The symptomatic adverse reactions produced by Sulfanilamide are more or less tolerable and if they become severe, they can be treated symptomatically, these include Allergic reactions, Itching, Burning discomfort.
Indications
Sulfanilamide is primarily indicated in conditions like Fungal infection, Meningitis, Pneumonia, Vulvo-vaginal candidosis.
Interactions
Sulfanilamide is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementChloroprocaineMestranolMethohexitone (Na)Phenytoin (Na)ProcaineDecreased effect of sulfonamides with the PABA metabolite of procaine. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Vag Cream, Vag Suppositories Store Below 40°C. Protect from Sunlight and Heat.
Warnings
Sulfanilamide should be used only if clearly needed during pregnancy or lactation. It should be used with caution in patients with any pre-existing kidney disease or allergies, especially to any antibiotics.
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