Simethicone

Simethicone has anti-foaming and water repellent properties. Simethicone is a mixture of dimethicones and silicon dioxide. Simethicone breaks gas bubbles in the digestive tract. iteffective as an adjunct therapy in condition in which gas is problem to relieve symptoms of excess gas such as air swallowing, dyspepsia, peptic ulcer, post-operative gaseous distention and irritable colon.


Adult Dose
Dose: 20 to 40 mg
Single Dose: 30 (30)
Frequency: 6 hourly
Route: PO
Instructions: After Meals and at bedtime
Neonatal
Paedriatic
Dose: 0 to 20 mg
Single Dose: 10 (10)
Frequency: As recommended.
Route: PO
Instructions: This dose should be taken 4 times a day by children of 2-12 years of age.
Characteristics
Simethicone also known as Dimethicone, Dimethicone, Dimethicone, Dimethicone. . It is of Synthetic origin and belongs to Silicondioxide. It belongs to Histamine (H-2) Antagonists and Antiflatulent pharmacological group.The Molecular Weight of Simethicone is 20500.00.
Contraindications
Simethicone is contraindicated in conditions like Allergy,Hypersensitivity to the drug,Hypersensitivity to any component of product.
Effects
The severe or irreversible adverse effects of Simethicone, which give rise to further complications include Rashes, Hives.The symptomatic adverse reactions produced by Simethicone are more or less tolerable and if they become severe, they can be treated symptomatically, these include Diarrhea, Constipation, Itching, Burning, Heart burn, Bloating, Stinging.
Indications
Simethicone is primarily indicated in conditions like Esophagitis, Flatulence, Gastric bloating, Gastrocardiac syndrome, Irritable bowel syndrome, Itchy dermatitis, Meteorism, Oesophagitis, Peptic ulcer, Postoperative gas pains, Skin irritations.
Interactions
Simethicone is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAlginic AcidThis interaction is sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required. Aluminium Hydroxide and OxideThis interaction is sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required. Strontium-89 ChlorideSaturation of bone-binding sites by calcium may reduce uptake of strontium-89 chloride. Moderate These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.
Interfrence
Risks
Drug should not be given to Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Drops Protect from Sunlight and Heat. Tab, Caps Store Below 40°C. Protect from Sunlight and Heat.
Warnings
Simethicone should be used with caution in patients with any pre-existing illness or allergy. It should be used only if clearly needed during pregnancy or lactation. Tell your health care provider if you have any medical conditions, especially if any of the following apply to you: if you are pregnant, planning to become pregnant, or are breast-feeding. If you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. If you have allergies to medicines, foods, or other substances. If you have an open wound, serious burn, or damaged, broken, or irritated skin. Do not get Dimethicone Cream in your eyes, nose, or mouth. If you get Dimethicone Cream in your eyes, rinse immediately with cool tap water. Wash your hands before and after using Dimethicone Cream unless your hands are a part of the treated area.
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