Silymarin

Silymarin is the active principle from the fruit of Silybum marianum. Silymarin is a free radical scavenger, used for the treatment of hepatic disorders.


Adult Dose
Dose: 200 mg
Single Dose: 200 (200)
Frequency: 12 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Dose: 20 to 40 mg/kg
Single Dose: 30 (30)
Frequency: 12 hourly
Route: Oral
Instructions:
Characteristics
belongs to Chromanones. It belongs to Cholagogues pharmacological group.
Contraindications
Silymarin is contraindicated in conditions like Hepatic encephalopathy,Primary biliary cirrhosis,Hypersensitivity to any component of product.
Effects
The signs and symptoms that are produced after the acute overdosage of Silymarin include Diarrhea.The symptomatic adverse reactions produced by Silymarin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Headache, Joint pain, Stomach upset.
Indications
Silymarin is primarily indicated in conditions like Hepatitis, Hepatitis A infection, Jaundice, and can also be given in adjunctive therapy as an alternative drug of choice in Cirrhosis.
Interactions
No data regarding the interactions of Silymarin was found.
Interfrence
Risks
Drug should not be given to Paediatrics, and Pregnant Mothers.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Tabs, caps, syrups Store in a well closed container, at room temperature, . Protect from Moisture and Heat.
Warnings
Should not be used by pregnant or breastfeeding women. People with a history of hormone-related cancers, including breast and uterine cancer and prostate cancer, should not take Silymarin. Should be use with caution in children.
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