Roxatidine

Roxatidine used in the management of peptic ulcer disease.


Adult Dose
Dose: 75 to 150 mg
Single Dose: 110 (112.5)
Frequency: 24 hourly
Route: PO
Instructions:
Neonatal
Paedriatic
Dose:
Single Dose:
Frequency:
Route:
Instructions: Not recommended in this age group
Characteristics
belongs to Piperidine. It belongs to H2-antagonist pharmacological group on the basis of mechanism of action. The Molecular Weight of Roxatidine is 384.90.
Contraindications
Roxatidine is contraindicated in conditions like Anuria.
Effects
The symptomatic adverse reactions produced by Roxatidine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Diarrhea, Restlessness, Constipation, Skin rashes, Nausea and vomiting.
Indications
Roxatidine is primarily indicated in conditions like GI ulceration, Hyperacidity, and can also be given in adjunctive therapy as an alternative drug of choice in Reflux oesophagitis.
Interactions
No data regarding the interactions of Roxatidine was found.
Interfrence
Increased hepatic enzyme concentrations.
Risks
Drug should not be given to patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.
Storage
Warnings
Roxitadine should be used with caution in patients with impaired kidney or liver function. Intravenous injection should be given slowly and intravenous infusion is recommended in patients with cardiovascular impairment.
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